Sep

4

Day: Tuesday                                                            14:45 – 16:30                                                                         Room: RB

week

Lerning Outcome

Focus study

 Topics

Subtopics

Learning methods

Lecturer

1 start on 7.9.2015 Understand basic concepts of human genetics Basic concepts of human genetics Role of lectureBasic concepts of human genetics

 

- Lecture and discussion F
2 Understand Mendelian inheritance patterns of the different types of inheritance patterns of human disease. Identify and  Compare a Mendelian inheritance pattern of different types of inheritance patterns of human disease Mendelian inheritance pattern of human disease Types of inheritance patterns of human disease Mendel law, single gene and polygenetics factors Sex-linked, multifactorial and maternal inheritance 

 

Presentation, Lecture and discussion, student homework F
3-4 Understand Gene-environment interaction in behavior related Genomics to the study of complex diseases Identifify Gene-environment interaction in behavior related Genomics to the study of complex diseases Mapping and characterizing “complex” genetic diseases Genomics for the study of complex diseases, genetic study of type 2 diabetes and obesity, Gene-environment interaction in behavior, pharmacogenetics Presentation, Lecture and discussion F
5-6 Understanding gene inheritance: Genes to proteins to traits Identify Gene to protein synthesis Transcription, post-transcription (mRNA maturation)  and translation , post-translation (functional protein modification) how a gene provides the instructions for making a protein and how genes can cause albinism or sickle cell anemia or other disease Presentation, Lecture and discussion 

student homework

WN
6-8 Understand multigenic inheritance patterns. Identify a multigenic inheritance pattern. Mapping and characterizing “simple” genetic disease Mapping disease genes, disease-associated mutations, diseases associated with a gene loss-function effect, nuclear and mitochondrial genome mutations,  Evolution of a gene cluster and divergence of function Presentation, Lecture and discussion 

student homework

WN

MIDDLE SEMESTER EXAMINATION

9-10 Understand the current research into epigenetic and transgenerational inheritance. Explain the basics of epigenetic and transgenerational inheritance. Sex, prions, and epigenetics Epigenetic inheritance of chromatin states / Role of DNA methylation in human disease,dysregulation of the histone modification machinery, transgenerational epigenetic inheritance, sex determination,  prion diseases Presentation, Lecture and discussion 

student homework

WN
11-12 Understand  how to interpret data from a genome-wide association (GWA) study and Genetic Testing Analyze data from genome-wide association studies. Genome-wide association (GWA) study and Genetic Testing Genome-wide association (GWA) studyType, across the life span (prenatal, pediatric and adult), technology, molecular, clinical and ethical perspectives Presentation, Lecture and discussion 

student homework

WN
13 Understand Chromosomal and genomic disorders Identify Chromosomal and genomic disorders Chromosomal and genomic disorders Mechanisms and maternal age influence the origin of aneuploidy in humans, mechanisms causing these aberrations, fragile X syndrome Presentation, Lecture and discussion 

student homework

F
14 Understand the potential implications of personalized and genomic medicine Explain the potential benefits and risks/challenges of genomic medicine. Natural genetics resources: the potential benefits and risks/challenges Pharcogenenomic and/orNutrigenomic:

Bioactive compound, phytopharmaca, functional food for healthy controlling

Presentation, Lecture and discussion 

student homework

F
15 Understand some of the ethical issues facing genomic researchers. Explain some of the ethical challenges raised by the prevalence of genomic data Medical genetics and the associated ethical, legal, and social implications Ethical clearanceInform consent

ELSI for medical research based on samples of  human or animal model

Presentation, Lecture and discussion F

Lecturer: F (Prof. Fatchiyah, PhD) and WN (Prof. Wolfgang Nellen)

 


Daftar Pustaka

Rick Lewis. 2011. Basic Human Genetics. Routledge Taylor & Francis group, NY ·  ISBN-10: 0415579864 · ISBN-13: 978-0415579865,

 

Ricki Lewis. 2011. Human Genetics concepts and application. McGraw-Hill Education; 10 edition ISBN-13: 978-0073525303, ISBN-10: 0073525308 or ISBN: 007246268x

 

Tom Strachan & Andrew Read.2003. Human Molecular genetics. Garland Science; 3 edition. ·  ISBN-10: 0815341822 ·  ISBN-13: 978-0815341826

 

Julian Knight.2009. Human Genetic Diversity. Oxford Univrsity Press. London.

 

Robert Nussbaum, Roderick R. McInnes, and Huntington F Willard. 2007. Genetics in Medicine, 7th Edition. Sounders. ·  ISBN: 9781416030805

 

John Quackenbush. 2011. The Human Genome: Book of Essential Knowledge. ISBN-13: 978-1936140152

 

Bruce R. Korf  and Mira B. Irons. 2013. Human Genetics and Genomics. 4th Edition. Wiley-Blackwell. ISBN-10: 0470654473; ISBN-13: 978-0470654477

 

 

 

Sep

6

Matriks Rencana Pembelajaran Semester MK Genetika Manusia atau Genetika Medik.

 

Week

Lerning Outcome

Focus study

Pokok Bahasan

(topics)

Sub Pokok Bahasan

(subtopics)

Bentuk Pembelajaran

(Learning methods)

Indikator/Kriteria Penilaian

(Value Criteria)

Bobot Nilai

(%)

Fasilitas Pembelajaran

(learning Facility)

1 Understand basic concepts of human genetics Basic concepts of human genetics Lecture and discussion

6

Laptop, LCD, module
2 Understand Mendelian inheritance patterns of the different types of inheritance patterns of human disease. Identify and  Compare a Mendelian inheritance pattern of different types of inheritance patterns of human disease Mendelian inheritance pattern of human disease Types of inheritance patterns of human disease Mendel law, single gene and polygenetics factors Sex-linked, multifactorial and maternal inheritance Presentation, Lecture and discussion Kebenaran dan ketepatan analisis

6

Laptop, LCD, module, paper exam
3-4 Understand multigenic inheritance patterns. Identify a multigenic inheritance pattern. Mapping and characterizing “simple” genetic disease Mapping disease genes, disease-associated mutations, diseases associated with a gene loss-function effect, nuclear and mitochondrial genome mutations,  Evolution of a gene cluster and divergence of function Presentation, Lecture and discussion Kebenaran dan ketepatan analisis

18

Laptop, LCD, module, paper exam
5-6 Understand Gene-environment interaction in behavior related Genomics to the study of complex diseases Identifify Gene-environment interaction in behavior related Genomics to the study of complex diseases Mapping and characterizing “complex” genetic diseases Genomics for the study of complex diseases, genetic study of type 2 diabetes and obesity, Gene-environment interaction in behavior, pharmacogenetics Presentation, Lecture and discussion Kebenaran dan ketepatan analisis

16

Laptop, LCD, module, paper exam
6-8 Understand the current research into epigenetic and transgenerational inheritance. Explain the basics of epigenetic and transgenerational inheritance. Sex, prions, and epigenetics Epigenetic inheritance of chromatin states / Role of DNA methylation in human disease,dysregulation of the histone modification machinery, transgenerational epigenetic inheritance, sex determination,  prion diseases Presentation, Lecture and discussion Kebenaran dan ketepatan analisis

12

Laptop, LCD, module, paper exam
9-10 Understand Chromosomal and genomic disorders Identify Chromosomal and genomic disorders Chromosomal and genomic disorders Mechanisms and maternal age influence the origin of aneuploidy in humans, mechanisms causing these aberrations, fragile X syndrome Presentation, Lecture and discussion Kebenaran dan ketepatan analisis

12

Laptop, LCD, module, paper exam
11-12 Understand the potential implications of personalized and genomic medicine Explain the potential benefits and risks/challenges of genomic medicine. Natural genetics resources: the potential benefits and risks/challenges Pharcogenenomic and/orNutrigenomic:

Bioactive compound, phytopharmaca, functional food for healthy controlling

Presentation, Lecture and discussion Kebenaran dan ketepatan analisis

6

Laptop, LCD, module, paper exam
13 Understand some of the ethical issues facing genomic researchers. Explain some of the ethical challenges raised by the prevalence of genomic data Medical genetics and the associated ethical, legal, and social implications Ethical clearanceInform consent

ELSI for medical research based on samples of  human or animal model

Presentation, Lecture and discussion Kebenaran dan ketepatan analisis

6

Laptop, LCD, module, paper exam
14-15 Understand how to interpret data from a genome-wide association (GWA) study and Genetic Testing Analyze data from genome-wide association studies. Genome-wide association (GWA) study and Genetic Testing Genome-wide association (GWA) studyType, across the life span (prenatal, pediatric and adult), technology, molecular, clinical and ethical perspectives Presentation, Lecture and discussion Kebenaran dan ketepatan analisis

16

Laptop, LCD, module, paper exam

 

Daftar Pustaka

Rick Lewis. 2011. Basic Human Genetics. Routledge Taylor & Francis group, NY ·  ISBN-10: 0415579864 · ISBN-13: 978-0415579865,

Ricki Lewis. 2011. Human Genetics concepts and application. McGraw-Hill Education; 10 edition ISBN-13: 978-0073525303, ISBN-10: 0073525308 or ISBN: 007246268x

Tom Strachan & Andrew Read.2003. Human Molecular genetics. Garland Science; 3 edition. ·  ISBN-10: 0815341822 ·  ISBN-13: 978-0815341826

Julian Knight.2009. Human Genetic Diversity. Oxford Univrsity Press. London.

Robert Nussbaum, Roderick R. McInnes, and Huntington F Willard. 2007. Genetics in Medicine, 7th Edition. Sounders. ·  ISBN: 9781416030805

 

Atau pustaka yang terbaru sesuai dengan materi kuliah